Restoration of Vision after Crossing of Optic Nerves and after Contralateral Transplantation of Eye

IN REGENERATION of the optic nerve in amphibians the ingrowing optic axons, despite extreme intertangling and disarrangement of their original intraneural pattern in the scar region, manage somehow to restore their former functional associations in the brain centers in a discriminate systematic manner. Central synaptic connections are selectively reestablished by the various regenerating fibers in accordance with the specific location of their ganglion cell bodies in the retinal field. This orderly restoration of central reflex associations is predetermined in the regeneration process itself and is not aided by, nor subject to, any functional as learning. readaptation process such